Luckily the only thing I've done so far happened with the 60mm Meade, and it at least didn't end up being a problem.
I was trying out some of my Orion EPs on the Meade 60mm refractor, and I wanted to see how the cheap giveaway Barlow that came with the 60mm would compare to my Orion Shorty Barlow. When I went to put the Shorty in, the thumbscrew in the focuser needed to be loosened a little, and I loosened it too quickly, causing the thumbscrew to come all the way out and drop in the grass.
It took me about 15 or 20 minutes to find it with a bright flashlight, but I did finally see it, so no harm done