Thank you very much for sharing your results with us! I'm glad you are making good progress.
How often did you check the alignment during the panorama recording? And how precisely did the telescope return to the landmark at those alignments? It is essential to monitor the alignment throughout the session unless you have a really high-precision mount with absolute encoders (such as the 10Micron mounts) which is aligned properly with celestial north. If I repeat the alignment often enough, and drift correction is active, I never see gaps between the tiles.
If it is not too inconvenient for you I would recommend that you do the camera rotation. If the orientation is wrong, gaps between tiles could be the result. In your example, however, I doubt that this was the primary reason.
Even with high enough overlap values, gaps could be the result of a wrong value for focal length. Sometimes it is difficult to find out the focal length of the whole imaging system. If the f value is set too low, MoonPanoramaMaker will use too few tiles. Of course, one can correct this by either increasing the value for focal length, or overlap size.
I never saw a decrease in FC frame rate on my computer when I switched on the plugin. Of course, you could run MPM in semi-automatic mode. To do this, you set "camera automation" to "False". You then have to start the videos in FC by hand when asked by MPM to do so. I would prefer this solution to binning.
I'm looking forward to seeing your next results!
All the best,