I've had this issue in the past and I cannot figure out how to correct it... I use SkyX Software for imaging and guiding. I have a ZWO1600 mono for imaging and a ZWO 120 mono for guiding. When you first set up the gear with the software for the first time, you have to choose the camera for each part (imaging and guiding) from a drop down. There is just one generic dropdown titled ASICamera for both camera.
When I first set up the system(last year) I made it thru this issue. Now, something has changed and the software is confused on what camera to 'talk to' when guiding or imaging. The guiding software in SkyX keeps connecting to the imaging camera... It's very frustrating especially considering I remember having this issue in the past and fixing it then.
Thanks in advance to whomever has advice.