I have the ASI294MC Pro. So far I am very pleased with it. It has exceeded my expectation. I set it at 570 gain and 1 second and I saw the whole Orion Nebula.
It is really that sensitive, especially with cooling. Of course using higher gains reduces color dynamics. I usually use 300 to 350 gain.
I find the cooling very useful, even at short exposures. Dark framing with cooling helps a lot.
I am nothing but pleased with the camera. I need more practice and I will get better.