Okay, so you are using NexRemote via a connection to the bottom of the NexStar+ hand control, correct? As I note in this article at my website:
(reachable via the NexStar+ article and the upgrade article) no response errors are a known issue when the NexStar+ hand control has newer firmware. That would probably also be the case when using NexRemote via the NexStar+ hand control.
So, start with the regular NexStar+ upgrade instructions I have here:
but prior to actually performing the update on the HC, go back to:
and follow those directions to load version 5.22.3280. That should eliminate the no response errors, both when using the hand control itself or when using NexRemote connected via the hand control.
The only caveat is that this older version does not have the fix for the GPS rollover issue:
It is possible your original equipment NexStar GPS mount does not have that issue. If not, then you should be all set. If your mount does set the date 19.7 years in the past after a GPS link, then the best bet is to keep looking for a version 4 hand control as that does fix the GPS issue (when loaded with version 4.22 firmware). Or as long as the no response errors are gone, you could use version 4.22 inside of NexRemote.