I think it's very much a matter of personal preference, and a question of how much time you're willing/able to devote to one target.
I rarely take SII images; only when I've seen an SHO version of something that I find attractive. I sometimes will take only Ha and OIII, when I don't think an SHO would be interesting, but I know it has strong OIII emissions (so an HOO might be nice, and/or enhancing the RGB with Ha and OIII will be nice).
And sometimes I'll take all three sets of NB images, and process the data in different ways.
In my experience, most bright emission nebulae have a significant amount of Ha (obviously) and OIII, and most have enough SII that one can make a pretty SHO photo if desired (but, in the interest of full and fair disclosure, most pretty SHO images have done two things that might not be obvious: (i) applied HLVG/SCNR to turn the green--the dominant color on most SHO images when realistically balanced, since Ha is the dominant emission--to a tan, and (ii) boosted SII and OIII so they make a colorful image, instead of one dominated by Ha.
There are lots of SHO images of M8 on the Web.
You'll figure out what pleases you (which, IMO, should be any imager's primary goal) with some experience.
Edited by WebFoot, 13 July 2020 - 05:41 PM.