It depends on what the seeing problem is. As a general rule, the first thing to try is to look for targets that are directly overhead so that you are looking through less air.
Some times, especially in the summer, high level haze moves in, and although there are no clouds in the sky, it takes longer exposures to get the same results. If it gets too bad, the only option is to give up.
If low level fog moves in, then its time to quit.
If skies are turbulent, as in stars are jumping around, then reduce sub-exposure times and turn on FWHM and brightness filtering. Also look for targets, such as large nebula, that need less resolution. In this case, fast focal ratios, short focal lengths and mono cams have an advantage. This is a common problem for me. So I keep a small fast scope piggy backed to my large scope. Right now, it is a 6in imaging Newt that is reduced to f3. For example, last night I had very clear skies, but the stars were jumping around in my large scope (16in f5 2000mm fl). I switched to overhead targets, dropped sub-exposures to less than 1 second and set the filters to screen out bad subs. Even then, I wasn't getting the resolution that I wanted. So I switched to the smaller scope and checked out a nebula.