I have a Canon 5D Mk IV
A shutter release cable is so you don't jiggle camera while getting a photo. If you don't have one, you can use the shutter release timer instead.
Mirror lock up is the avoid jiggling the camera when the camera shutter is activated to get a picture, and the mirror is moving out of the way. I think I used it for last time I photographed the eclipse.
ISO 400 might be okay depending on your lens aperture and shutter speed settings. The last time I shot a lunar eclipse with a Canon DSLR and EF 300mm lens, I used f4, 2 seconds at ISO 1600 at the peak of the eclipse while the camera and lens rode piggyback on the telescope. The scope was well polar aligned and so autoguiding was unnecessary. No harm in using it, if you already have it. I assume you are not shooting through the telescope but using it for tracking.
If you are using the telescope for your lens, all you lose is the ability to set the aperture value. But the whole moon won't fit on the sensor, and you have to consider a mosaic.
Use your histogram to tell you the best settings. I think in live view mode, you can access the histogram, and the mirror will already be in lock-up position. But live view mode is a battery drainer. Hope you have spares. Or you can shut the camera off between shots. Figure the phases take around 3 hours. If you get a shot every 10 minutes, that's 6 per hour and 18 total. At each interval, get extra shots in case you blew it on one.
And you're not going to damage the sensor. It's reflected light.